SKC OSHA/NIOSH/ASTM Sampling Guide for 2,4- TDI (Toluene diisocyanate) (isocyanates)

Chemical Hazard

2,4- TDI (Toluene diisocyanate) (isocyanates)

CAS. No.


Sampling Methodology

OR-OSHA 1010

Sampling Parameters

Agency Standards (ppm)




TWA 0.02

45 L

1000 ml/min

45 min

C/STEL 0.005

5 L

1000 ml/min

5 hrs

Analytical Method


SKC Sampling Equipment


Impinger Trap:225-22 

Coated Filter in Preloaded Cassette:225-9029 

Air Sampling Pump:220-5000TC 

Limit of Detection

approx. 0.03 ug/mL (LOQ)


OR-OSHA: Oregon OSHA method and target concentrations.
The MOPIP Derivatizing Solution, Cat. No. 225-9050, is needed to analyze for monomer/oligomer aerosol.

This SKC Air Sampling guide is a reference only to assist users in finding the method, sampling equipment, and sampling media for a specific compound. This publication is intended for general information only and should not be used as a substitute for reviewing applicable government regulations, equipment operating instructions, or legal standards. Users must consult the appropriate sampling method for the compound of interest before sampling. The sampling parameters shown here are suggestions based on the ranges or volume, flow, and time specified in the methods. It is the responsibility of the analyst performing the sampling and analysis steps to adjust the parameters so that the required detection limits can be obtained. The information contained in this document should not be construed as legal advice or opinion nor as a final authority on legal or regulatory procedures.

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